Doctoral (PhD) student position in translational medicine in rheumatology with a focus on B cell biology and antibody engineering

Doctoral (PhD) student position in translational medicine in rheumatology with a focus on B cell biology and antibody engineering

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Do You Want to Contribute to Top Quality Medical Research?

Becoming a doctoral student means dedicating yourself to a research project under the supervision of experienced researchers and following an individual study plan. A doctoral degree requires the equivalent of four years of full-time doctoral education.

The Research Group

The Division of Rheumatology at the Department of Medicine, Solna, is an active and internationally successful research unit. It conducts clinical, experimental, and epidemiological research in close collaboration with the rheumatology clinic at the Karolinska University Hospital, Solna. The division plays a leading role in several national and international consortia and networks. The research will be conducted in Dr. Caroline Grönwall’s group, which focuses on understanding the pathogenesis of autoimmune diseases, with a special interest in B-cells and autoreactive antibodies.

The Doctoral Student Project and Duties

We are seeking a motivated doctoral student with an interest in translational research, immunology, and molecular biology methodology. The project focuses on studies of autoantibodies and B cells in systemic lupus erythematosus (SLE). SLE is an autoimmune disease with multiorgan involvement and dysregulation of the adaptive immune system, particularly B cells. The student will study the role of B cells and autoantibodies in SLE pathogenesis through B cell phenotyping, serological screening, BCR repertoire and single-cell analysis, and the generation of monoclonal antibodies from patient B cells. The applicant should be enthusiastic about research and translational medicine. The doctoral student will perform practical laboratory work, contribute to experimental design, optimize methods, analyze data, and present results. The student will also participate in courses, seminars, and conferences.

What We Offer

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world's leading medical universities. Our vision is to advance knowledge about life and promote better health for all. At Karolinska Institutet, we conduct successful medical research and offer the largest range of medical education in Sweden. As a doctoral student, you will have an individual research project, a well-educated supervisor, a wide range of elective courses, and the opportunity to work in a leading research group. Karolinska Institutet collaborates with prominent universities worldwide, providing opportunities for international exchanges. You will be employed on a doctoral studentship, which includes a contractual salary. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Eligibility Requirements for Doctoral Education

To participate in the selection for a doctoral position, you must meet the following general (A) and specific (B) eligibility requirements by the application deadline.

A) General Eligibility Requirement

You meet the general eligibility requirement for doctoral/third-cycle/PhD education if you:

  1. Have been awarded a second-cycle/advanced/master qualification (i.e., master's degree), or
  2. Have satisfied the requirements for courses comprising at least 240 credits, of which at least 60 credits were awarded at the advanced/second-cycle/master level, or
  3. Have acquired substantially equivalent knowledge in some other way in Sweden or abroad.*

Follow the instructions on the web page Entry requirements (eligibility) for doctoral education.

*If you claim equivalent knowledge, follow the instructions on the web page Assessing equivalent knowledge for general eligibility for doctoral education.

B) Specific Eligibility Requirement

You meet the specific eligibility requirement for doctoral/third-cycle/PhD education if you:

  • Show proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school.

Follow the instructions on the web page English language requirements for doctoral education.

Verification of Your Documents Karolinska Institutet checks the authenticity of your documents. Admission may be revoked if supporting documents are found to be fraudulent. Submission of false documents is a violation of Swedish law and is considered grounds for legal action.

(A) and (B) can only be certified by the documentation requirement for doctoral education.

Skills and Personal Qualities

The applicant should have a background in biotechnology, medicine, or biomedicine and a strong interest in immunology. Practical experience with techniques such as PCR, protein engineering, antibody assays, transcript analysis, cell culture, and/or flow cytometry is expected. Knowledge in data analysis and bioinformatics is also beneficial. The applicant must be willing to work with human blood and tissue samples. The doctoral student is expected to design and perform experiments rigorously and transparently. A successful candidate should be open to learning new methods, be responsible, have a positive attitude, function well in a team environment, and possess good problem-solving and independent work abilities. Strong communication skills and proficiency in written and spoken English are necessary.

Terms and Conditions

The doctoral student will be employed on a doctoral studentship for a maximum of 4 years full-time.

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Application Process

Submit your application and supporting documents through the Varbi recruitment system. Use the button in the top right corner and follow the instructions. We prefer that your application is written in English, but you can also apply in Swedish.

Your application must contain the following documents:

  • A personal letter and a curriculum vitae
  • Degree projects and previous publications, if any
  • Any other documentation showing the desirable skills and personal qualities described above
  • Documents certifying your general eligibility (see A above)
  • Documents certifying your specific eligibility (see B above)

Selection

A selection will be made among eligible applicants based on the ability to benefit from doctoral education. The qualifications of the applicants will be evaluated on an overall basis.

Karolinska Institutet uses the following bases of assessment:

  • Documented subject knowledge of relevance to the area of research
  • Analytical skill
  • Other documented knowledge or experience that may be relevant to doctoral studies in the subject

All applicants will be informed when the recruitment is completed.

Location

The position is located within the Department of Medicine, Solna. The department consists of twelve divisions, each with several research groups. The position is within the research group of Caroline Grönwall at the Division of Rheumatology.

https://ki.se/en/research/research-areas-centres-and-networks/research-groups/b-cells-and-autoantibodies-in-rheumatic-disease-team-caroline-gronwall

Want to Make a Difference? Join Us and Contribute to Better Health for All

Type of Employment:
Contract Type:
Number of Positions:
Full-time Equivalent:
City:
County:
Country:
Reference Number:
Contact: Caroline Grönwall, caroline.gronwall@ki.se

Union Representative:

  • Maria Eldh, OFR, maria.eldh@ki.se
  • Louisa Cheung, SACO, Louisa.Cheung@ki.se
  • Farzad Hedayaty, SACO-s, farzad.hedayaty@ki.se

Published:
Last Application Date:

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Job Overview

Doctoral (PhD) student position in translational medicine in rheumatology with a focus on B cell biology and antibody engineering